MILWAUKEE (AP) — Markus Howard scored 38 points and No. 10 Marquette hung on at the buzzer, edging No. 14 Villanova 66-65 Saturday and handing the Wildcats their first Big East Conference loss.

Marquette (20-4, 9-2) led by 15 early in the second half. The Golden Eagles took a 66-63 lead on two free throws by Howard with 53 seconds left, but Phil Booth answered with a floater in the lane that made it a one-point game.

Jermaine Samuels then stripped Howard on the ensuing possession with 14 seconds left. After a timeout, Booth drove but was trapped underneath, and passed the ball back to Samuels, who missed an off-balance jumper from the left side as time ran out.

Booth had 19 points and Eric Paschall 17 for Villanova (19-5, 10-1), which had won 11 straight since a 74-71 loss to Kansas on Dec. 15.

Howard hit 13 of 24 shots, including 5 of 11 on 3s. He made all seven of his free throws.

Marquette bounced back from its first home loss of the season, a 70-69 loss to St. John’s on Tuesday. Sacar Anim added 18 for the Golden Eagles.

The Golden Eagles opened the second half with a 10-3 run, taking a 40-29 lead on a jumper by Sam Hauser with 16:38 left. Marquette pushed the lead to 47-32 on Anim’s jumper as Villanova made just 2 of its first 12 shots after the break.

Villanova answered with 10 consecutive points, pulling within 47-42 on Saddiq Bey’s 3-pointer from the right corner. The Wildcats later went on a 13-2 burst and took a 55-53 lead on Samuel’s 3-pointer with 6:16 remaining.